According to the National Institute of Health (NIH), researchers at the Drexel University in Philadelphia funded by the Institute have developed a new ultrasound treatment technology that can effectively cure varicose ulcers , Is expected to open up new ways for the treatment of chronic trauma.

Varicose ulcers are caused by impaired valve function in venous blood vessels and blood backflow obstruction, which accumulates in the blood vessels, causing the blood vessels to deform and flex, protein and cells penetrate into the tissues around the blood vessels, forming inflammation and ulcers. Such ulcers are the main cause of extremity wounds. Traditional treatment methods are not ideal, including controlling local swelling, keeping the wound moist, preventing infection and compression (patients wear elastic stockings to prevent venous reflux), etc. Patients usually take months It will take years to recover.

Researchers at Drexel University have developed a new varicose ulcer treatment technique. They use 20KHZ (low frequency), low-intensity ultrasound to irradiate patients with varicose ulcer for 15 minutes a week. Recovery, the treatment effect was significantly improved compared to the control group. The in vitro experiments in mice further confirmed the above findings. The researchers irradiated the mice with 20KHZ ultrasound for 15 minutes and tested fibroblasts (an important factor to promote wound healing) after 24 hours. Compared with the control group, the rats in the experimental group were metabolized by fibroblasts Increase by 32%, increase by 40%.

In order to facilitate the practical application and promotion of this technology, the researchers also developed early treatment monitoring accessories, non-invasive monitoring of the wound surface by near-infrared spectroscopy, the treatment effect can be evaluated early in the treatment of ultrasound, and the doctor can adjust the treatment method in time. It also provides a reliable guarantee for other types of trauma patients to develop personalized ultrasound treatment programs. In addition, the researchers will develop a portable ultrasound treatment device. The patient is connected to two rechargeable lithium batteries through an ultrasound patch that weighs about 100 grams and can be treated at home.

Researchers are further conducting clinical trials. If the effectiveness and safety of the technology are verified, it may be used in the treatment of chronic wounds such as diabetes and pressure ulcers in the future.

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