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Shanghai Xinzhuang Instrument Co., Ltd. is a leading domestic manufacturer of scientific instruments, known for its energy-efficient and environmentally friendly LNB brand centrifuge. With a focus on professional manufacturing, the company offers high-quality products that are both secure and cost-effective. The selection of premium materials, combined with meticulous craftsmanship, ensures excellent performance at a reasonable price. Since its establishment, the company has consistently invested in product development, upgrades, and innovation, introducing intelligent instruments that are easy to operate and highly stable. This commitment to quality and user satisfaction remains at the core of Xinzhuang Instruments’ philosophy.
To better serve its customers, the company employs experienced application engineers who are always available to provide technical support and answer any questions you may have. Based on its independent research and development capabilities, Shanghai Xinzhuang Instrument has developed a wide range of scientific equipment, including low-temperature constant temperature devices, ultrasonic instruments, box-type instruments, microbial instruments, ice-making refrigeration units, and laboratory accessories. Over time, the company has established a comprehensive product development strategy, focusing on various scientific technologies and applications.
One of the key technologies developed by the company is the solid phase extraction (SPE) system under the LNB brand. Since the introduction of SPE in the late 1970s, there has been rapid progress in the development of SPE columns with different stationary phases. As a result, SPE has become increasingly adaptable to the pretreatment needs of various sample types, with methods continuously refined for different compounds.
Solid Phase Extraction is a sample preparation technique that uses a solid adsorbent to selectively retain target compounds from a liquid sample, removing them from the matrix and interfering substances. The compound is then eluted or desorbed using an appropriate solvent, enabling effective separation and concentration. As a widely used method in laboratories, SPE plays a crucial role in improving analytical accuracy and efficiency.
Although SPE shares similarities with High-Performance Liquid Chromatography (HPLC) in terms of separation mechanisms and stationary phase selection, it differs significantly in particle size and column design. SPE columns typically use particles larger than 40 µm, compared to HPLC’s 3–10 µm, resulting in lower efficiency. A single SPE column may only produce 10–50 theoretical plates, while an HPLC column can generate over 10,000. Therefore, SPE is more suitable for sample purification rather than complex separations. It often operates in a digital switching mode, where the analyte is either not retained or fully eluted through a stepwise gradient.
Another key difference is that SPE columns are usually disposable, making them ideal for one-time or routine sample preparation tasks. Despite its lower separation efficiency, SPE is highly valuable for several purposes:
1. Removing interferences that could affect subsequent analysis
2. Concentrating trace components to enhance detection sensitivity
3. Changing the solvent to match the analytical method
4. Performing in situ derivatization
5. Removing salts from the sample
6. Simplifying sample storage and transportation
Among these, purification and enrichment are the most critical functions of SPE technology.
Shanghai Xinzhuang Instrument Co., Ltd. continues to innovate and improve its SPE systems, ensuring they meet the evolving needs of modern laboratories. If you're interested in learning more about their products or would like to discuss your specific requirements, feel free to contact us at [http://www.xinzhuang.com](http://www.xinzhuang.com).