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Shanghai Xinzhuang Instrument Co., Ltd. has developed an advanced automatic solid phase extraction device, available in 12- and 24-well configurations, offering unified control with individual well management. This technology is a powerful sample preparation method that uses a solid adsorbent to capture target compounds from a sample, effectively removing matrix interferences. The analytes are then eluted using appropriate solvents, making it an essential tool for sample purification and concentration. Building on traditional liquid-liquid extraction (LLE), this technique leverages the principles of chromatography, including those used in high-performance liquid chromatography (HPLC) and gas chromatography (GC).

The process of solid-phase extraction relies on the stronger affinity of the target compound for the solid sorbent compared to the sample matrix. As the sample flows through the SPE column, the analyte binds to the stationary phase while other components pass through. A suitable solvent is then used to elute the desired compounds. There are four main types of SPE: reverse-phase (RP-SPE), normal-phase (NP-SPE), ion-exchange (IE-SPE), and adsorption-based SPE. It is commonly used for processing liquid samples to extract, concentrate, and purify volatile and semi-volatile compounds. For solid samples, they must first be converted into a liquid form before SPE can be applied.

As the number of SPE operations increases, manual handling becomes time-consuming and prone to errors, which can significantly affect the reproducibility of results. To address these challenges, Shanghai Xinzhuang introduced vacuum manifold technology from the U.S., enabling efficient batch processing of multiple SPE samples simultaneously. The DG series solid-phase extraction device ensures no cross-contamination and features a closed, transparent observation chamber for clear visibility during the process. This not only improves efficiency but also enhances accuracy and reliability in analytical work.

In addition to its advanced SPE systems, Shanghai Xinzhuang has developed a wide range of laboratory instruments, including low-temperature constant temperature devices, ultrasonic equipment, box-type instruments, microbial testing tools, ice-making refrigeration units, and supporting lab equipment. The company continues to expand its product portfolio, focusing on scientific instrument innovation and technological development. We welcome all customers to explore our comprehensive solutions tailored to meet diverse laboratory needs.

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